Practical Proteins (Part 4 of 4)
by Mollie Grove
In this lesson students will use everything they've done in parts 1-3 to analyze how mutations affect proteins. Students will build the mutated proteins that they sequenced in part 3. They will test or attempt to test each mutated protein to see if it can still perform its functions. As they test each mutated protein, they will describe how the mutation affected its ability to function. After testing the mutated proteins, students will use the modified codon chart to calculate the probabilities of how likely different mutations are to cause a protein to lose its ability to function.